Endocrine Abstracts

Objective: Diabetic retinopathy was one of the important complications of diabetes both in type 1 or type 2 and cause blindness. High lipid levels was accused of endotheial dysfunction and so play a role in retinal exudate formation in retinopathy. The aim of this study was to acess the association between serum lipid levels and diabetic retinopathy.Methods: Our study was carried out retrospectively in Istanbul Medeniyet University Goztepe Training and R...

Objectives: Diabetic nephropathy is a common complication of diabetes. It can be a cause of abnormal lipoprotein metabolism and may be had an negative impact on metaboic control in diabetics. The aim of this study was to evaluate the effect of diabetic nephropathy on lipid profiles of adult type 1 diabetics.Methods: Our study was carried out retrospectively in Istanbul Medeniyet University Goztepe Training and Research Hospital between 2012 and 2013. The...

Graves’ disease (GD) is an autoimmune disease caused by autoantibodies binding to and activating the thyroid-stimulating hormone receptor (TSHR). Chronic stimulation of the TSHR results in a hyperactive thyroid gland and hyperthyroidism. The purpose of this study was to determine the association between Rho-kinase (ROCK1 and ROCK2) gene polymorphisms and GD in a Turkish population. A total of 142 patients with HT and 163 healthy control subjects were in...

Graves’ disease (GD) is an organ-specific autoimmune disorder of the thyroid due to the presence of circulating anti-thyroid-stimulating-hormone receptor stimulating autoantibodies that lead to hyperthyroidism. Involvement of the genetic variants of RHO genes in GD has not been examined yet. Therefore, the aim of this study was to investigate possible associations between RHO gene polymorphisms and GD in a Turkish population. A total of 128 patients with GD and ...

Background and aim: Although insulinoma typically causes fasting hypoglycemia, postprandial hypoglycemia occasionally reported in these patients. We aimed to report a rare case of insulinoma who atmitted to outpatient clinic with postprandial hypoglycemia.Case report: A 31-year-old woman was admitted to outpatient clinic with postprandial hypoglycemia. Capillary blood glucose levels were found 25 and 27 mg /dl during typical hypoglycemic symptoms such as...

Background: We aimed prospectively investigate the laboratory and electrocardiographic parameters (hearth rate, QRS, QT, QTc, Tpe, Tpe/QTc, arrhythmia prevalance) in patients with graves disease before and after antithyroid therapy.Methods: 71 patients (48 female, 23 male), age between 18–50 (mean ± s.d.: 36.48 ± 12.20) with GD were included into the study. Patients treated with antithyroid therapy (thionamids and/or surgical the...

Background: The results of studies evaluating the relationship between serum 25-hydroxyvitamin D (25OHD) with intact PTH (iPTH), calcium (Ca) and phosphorus (P) levels are controversial.Objective: To determine the diagnostic values of iPTH, Ca and P for the prediction of vitamin D deficiency.Methods: We analysed iPTH, Ca and P levels in otherwise healthy 700 subjects (619 (88.4%) female, 81 (11.6%) male, mean age 47.44±16.58 y...

Case report: A 56-year-old woman admitted to emergency department with fever, dyspnea, productive cough, palpitations, diffuse myalgia, and malasia. Physical examination revealed an anxious-appearing woman with fine tremor in the hands. Her pulse was 140 beats/minute and irregular; blood pressure, 140/90 mmHg; temperature 38.6 °C, respiratory rate 40 breaths per min, and oxygen saturation 91% without supplemental oxygen. In auscultation, bilaterally rales and bronchial br...

Cytokines play a crucial role in the pathogenesis of autoimmune thyroid disease, and recent studies have demonstrated an association between cytokine gene polymorphisms and Graves’ disease (GD) in different ethnic groups.The aim of the present study was to investigate the relationship of IL-6, IL-10, TNF-α, TGF-β, and INF-γ gene polymorphisms with the development of GD in Turkish population. A total of 224 subjects were included in the study comprising of 1...

Background: Primary hyperparathyroidism (PHPT) is associated with various musculoskeletal complaints. It is difficult to evaluate muscle strength as it is hard to extract objective data due to lack of definite methods for measurement.Objective: To assess the differences between PHPT patients and healthy controls regarding maximum foot force and plantar pressure distribution by using platform pressure measuring system [Footscan (RSscan)].<p class="abs...